Opioids are the most powerful painkillers we have, but they’re incredibly addictive. Tens of thousands of people in the U.S. die of an opioid overdose every year. Will we ever have drugs that are just as good at getting rid of pain but without the risk of addiction and overdose?
- Sources:
Frederich Serturner
Opioid toxicity
Opioid overdoses--world stats
Opioid death rates in the US
Inside the Story of America’s 19th-Century Opiate Addiction
Abuse-deterrent opioids
NIH solicits research into vaccines that protect against opioid use - Vaccines against addictive drugs push forward despite past failures
Looking beyond opioids for safer pain relief
Opioid abuse timeline (FDA)
Overdose death rates
Prostaglandins
God’s Own Medicine
Heroin
Ibuprofen
Oxycodone
Heroin chapter
Structure of ibuprofen bound to COX-2
Use of Oxycodone in Pain Management - Overcoming opioids: The quest for less addictive drugs
Rats prefer sugar to heroin
NIDA heroin info
Heroin History
Frontline PBS: Opium throughout history
The Ongoing Opioid Prescription Epidemic: Historical Context
Heroin’s Addiction’s Fraught History
Heroin Prescription and History
Addiction medications
Opiate history
Death Tolls
Overdose Increases
Etanercept
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