Irving S. Sigal Postdoctoral Fellowship

The Irving S. Sigal Postdoctoral Fellowship (Sigal Fellowship) of the American Chemical Society (ACS) is a two-year postdoctoral fellowship awarded every two years to a Ph.D. candidate who will pursue research at the chemistry and biology interface. Candidates are nominated by chairs of PhD-granting Chemistry Departments in the United States. Individuals are not able to submit an application without being nominated.


The Irving S. Sigal Postdoctoral Fellowship provides two years of financial support for a scientist who has earned or will earn a doctoral degree in chemistry during the academic year of the competition or the preceding year in a graduate chemistry department within the United States and who wishes to pursue in chemistry postdoctoral research at the biology-chemistry interface. There are no restrictions on the age or nationality of the fellow. The Sigal Postdoctoral Fellowship currently provides $50,000 per year for two years of research at one or more non-profit institutions in any country.

Nomination Process

During a competition, approximately one-fifth of the US doctoral chemistry departments are invited to nominate one candidate for the Sigal Postdoctoral Fellowship. Applications are reviewed and rated by a panel, and announcement of the Sigal Awardee is anticipated by late June of the competition year. It is expected that the fellow will commence the two years of postdoctoral study by January 1st of the following year.

Dr. Irving S. Sigal

The Sigal Fellowship, established by Dr. Irving S. Sigal’s widow, Dr. Catherine T. Sigal, has two purposes. The first is to honor the memory of Dr. Irving S. Sigal, a brilliant young biochemist who died in 1988 as a passenger aboard Pam Am flight 103. The second purpose is to advance research at the chemistry and biology interface where Dr. Sigal’s seminal work made critical advances which will have enormous influence for decades.

Dr. Irving S. Sigal was a talented and promising research chemist who was one of the pioneers in applying site-directed mutagenesis to study the structure and function of enzymes and proteins. In 1995, his widow, Dr. Catherine T. Sigal, provided funding through the American Chemical Society to establish a postdoctoral fellowship in his memory.